About Ulcerative Colitis

What is Ulcerative Colitis?

Ulcerative colitis is a type of inflammatory bowel disease (IBD) that causes inflammation and ulcers in the inner lining of the large intestine (colon) and rectum. Symptoms of ulcerative colitis can include abdominal pain, diarrhea, rectal bleeding, and weight loss. Treatment for ulcerative colitis typically involves medications, lifestyle changes, and in some cases, surgery.

What are the symptoms of Ulcerative Colitis?

The most common symptoms of ulcerative colitis include:

-Diarrhea (often bloody)
-Abdominal Pain and cramping
-Fever
-Fatigue
-Weight loss
-Loss of appetite
-Rectal pain
-Rectal bleeding
-Urgency to have a bowel movement
-Inability to have a bowel movement
-Nausea
-Anemia
-Joint pain
-Skin lesions

What are the causes of Ulcerative Colitis?

The exact cause of ulcerative colitis is unknown, but it is believed to be a combination of genetic, environmental, and immunological factors. Genetic factors may play a role in the development of ulcerative colitis, as it is more common in people with a family history of the condition. Environmental factors, such as certain foods, stress, and infections, may also contribute to the development of ulcerative colitis. Finally, an abnormal immune response may be involved, as the body’s immune system may mistakenly attack the cells of the digestive tract.

What are the treatments for Ulcerative Colitis?

1. Medications:

-Aminosalicylates (5-ASAs): These medications reduce inflammation in the colon and rectum. Examples include mesalamine (Asacol, Pentasa, Lialda), balsalazide (Colazal), and olsalazine (Dipentum).

-Corticosteroids: These medications reduce inflammation and suppress the immune system. Examples include prednisone, budesonide (Entocort EC), and hydrocortisone (Cortenema).

-Immunomodulators: These medications suppress the immune system and reduce inflammation. Examples include azathioprine (Imuran), mercaptopurine (Purinethol), and cyclosporine (Gengraf, Neoral, Sandimmune).

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What are the risk factors for Ulcerative Colitis?

1. Age: Ulcerative colitis is most commonly diagnosed in people between the ages of 15 and 30, although it can occur at any age.

2. Family history: Having a family member with ulcerative colitis increases your risk of developing the condition.

3. Smoking: Smoking increases your risk of developing ulcerative colitis and can make symptoms worse.

4. Ethnicity: People of Jewish descent have a higher risk of developing ulcerative colitis.

5. Stress: Stress can trigger flare-ups of ulcerative colitis symptoms.

6. Diet: Eating a diet high in processed foods and low in fiber may increase your risk of developing ulcerative colitis.

Is there a cure/medications for Ulcerative Colitis?

Yes, there are medications and treatments available for ulcerative colitis. These include anti-inflammatory medications, immunosuppressants, biologic therapies, and surgery. Your doctor will be able to discuss the best treatment option for you.