Progressive retinal dystrophy due to retinol transport defect (PRD-RDT) is a rare genetic disorder that affects the eyes. It is caused by a mutation in the gene that encodes the protein responsible for transporting retinol (vitamin A) from the liver to the retina. This mutation results in a deficiency of retinol in the retina, leading to progressive vision loss. Symptoms of PRD-RDT include night blindness, decreased visual acuity, and decreased color vision. Treatment is limited to vitamin A supplementation and supportive care.

The symptoms of Progressive Retinal Dystrophy due to Retinol Transport Defect (PRD-RDT) include:

-Night blindness
-Decreased vision in dim light
-Decreased color vision
-Decreased peripheral vision
-Loss of central vision
-Blind spots in the visual field
-Distorted vision
-Loss of contrast sensitivity
-Reduced visual acuity
-Photophobia (sensitivity to light)
-Floaters in the vision

1. Mutations in the gene responsible for the production of the protein retinol binding protein 4 (RBP4).
2. Mutations in the gene responsible for the production of the protein cellular retinaldehyde-binding protein (CRALBP).
3. Mutations in the gene responsible for the production of the protein lecithin retinol acyltransferase (LRAT).
4. Mutations in the gene responsible for the production of the protein retinol dehydrogenase (RDH).
5. Mutations in the gene responsible for the production of the protein retinol saturase (RS).
6. Mutations in the gene responsible for the production of the protein retinol isomerase (RIS).
7. Mutations in the gene responsible for the production of the protein retinol

1. Vitamin A supplementation: Vitamin A supplementation is the mainstay of treatment for progressive retinal dystrophy due to retinol transport defect. Vitamin A is essential for the normal functioning of the retina and supplementation can help slow the progression of the disease.

2. Low vision aids: Low vision aids such as magnifiers, telescopes, and closed-circuit television systems can help improve vision in those with progressive retinal dystrophy due to retinol transport defect.

3. Surgery: Surgery may be recommended in some cases to improve vision. This may include laser photocoagulation, vitrectomy, or retinal detachment repair.

4. Gene therapy: Gene therapy is a promising new treatment for progressive retinal dystrophy due to retinol transport defect. This involves introducing a healthy gene into the eye to replace

1. Family history of Progressive Retinal Dystrophy due to Retinol Transport Defect (PRD-RDT)
2. Genetic mutations in the RBP4 gene
3. Age
4. Exposure to certain environmental toxins
5. Vitamin A deficiency
6. Certain medications
7. Certain medical conditions, such as diabetes or high blood pressure

At this time, there is no cure for progressive retinal dystrophy due to retinol transport defect. However, there are medications that can help slow the progression of the disease. These medications include vitamin A supplements, antioxidants, and anti-inflammatory drugs. Additionally, some studies have suggested that gene therapy may be a potential treatment option in the future.