At this time, there is no cure for Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1. However, there are medications and treatments available to help manage the symptoms. These include growth hormone therapy, appetite suppressants, and medications to help with sleep disturbances, behavioral issues, and other medical problems. Additionally, physical, occupational, and speech therapy can help improve motor skills, communication, and daily living skills.

1. Low birth weight
2. Poor muscle tone
3. Feeding difficulties
4. Delayed motor development
5. Intellectual disability
6. Short stature
7. Hypogonadism
8. Behavioral problems
9. Sleep disturbances
10. Obesity
11. Hyperphagia
12. Skin picking
13. Speech and language delays
14. Scoliosis
15. Strabismus

1. Growth hormone therapy: Growth hormone therapy is the mainstay of treatment for Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1. Growth hormone therapy helps to increase muscle mass, reduce body fat, and improve overall physical development.

2. Nutritional management: Nutritional management is essential for individuals with Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1. This includes a balanced diet with adequate calories and nutrients, as well as regular monitoring of weight and food intake.

3. Behavioral therapy: Behavioral therapy is important for individuals with Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1. This includes strategies to help manage obsessive-compulsive behaviors, as well as techniques to help with communication and social skills.

4. Medications

1. Prader-Willi syndrome is caused by a genetic abnormality in the 15q11-q13 region of chromosome 15.

2. This abnormality is caused by a deletion of genetic material from the father's chromosome 15.

3. The deletion of genetic material can be either a complete deletion (type 1) or a partial deletion (type 2).

4. The deletion of genetic material from the father's chromosome 15 results in a lack of expression of certain genes in the 15q11-q13 region, which are necessary for normal development.

5. This lack of expression of certain genes leads to the physical and mental characteristics associated with Prader-Willi syndrome.

The most common symptoms of Prader-Willi syndrome due to paternal deletion of 15q11q13 type 1 include:

• Poor muscle tone
• Feeding difficulties in infancy
• Excessive appetite and obesity
• Intellectual disability
• Short stature
• Delayed development of motor skills
• Behavioral problems
• Sleep disturbances
• Speech and language delays
• Hypogonadism
• Scoliosis
• Strabismus
• Skin picking

Prader-Willi syndrome is a genetic disorder caused by a deletion of a specific region of chromosome 15, known as 15q11-q13. This deletion is usually inherited from the father, and is known as a paternal deletion. People with Prader-Willi syndrome typically have low muscle tone, short stature, cognitive disabilities, and a constant feeling of hunger that can lead to excessive eating and life-threatening obesity.