At this time, there is no known cure or medications for Pleuropulmonary blastoma familial tumor susceptibility syndrome. Treatment for this condition is focused on managing symptoms and preventing complications. Treatment may include surgery, chemotherapy, radiation therapy, and/or targeted therapy.

1. Family history of pleuropulmonary blastoma (PPB)
2. Genetic mutations in the TP53 gene
3. Exposure to radiation
4. Exposure to certain chemicals
5. Exposure to certain viruses
6. Low birth weight
7. Premature birth
8. Low socioeconomic status
9. Exposure to environmental toxins

There is no known cure for Pleuropulmonary blastoma familial tumor susceptibility syndrome. Treatment focuses on managing symptoms and preventing complications. This may include regular monitoring for signs of cancer, genetic counseling, and lifestyle modifications. Depending on the individual, treatments may also include chemotherapy, radiation therapy, and/or surgery.

Pleuropulmonary blastoma familial tumor susceptibility syndrome is caused by a mutation in the TP63 gene. This gene is responsible for the production of a protein that helps regulate cell growth and development. Mutations in this gene can lead to the development of pleuropulmonary blastoma, a rare type of cancer that affects the lungs and chest wall.

The symptoms of Pleuropulmonary blastoma familial tumor susceptibility syndrome vary depending on the type of tumor present. Common symptoms include:

-Respiratory distress
-Coughing
-Wheezing
-Shortness of breath
-Chest pain
-Fever
-Weight loss
-Fatigue
-Loss of appetite
-Abdominal pain
-Blood in the sputum
-Recurrent infections
-Enlarged lymph nodes
-Abnormal chest X-rays
-Abnormal CT scans
-Abnormal MRI scans
-Abnormal echocardiograms
-Abnormal pulmonary function tests

Pleuropulmonary blastoma familial tumor susceptibility syndrome (PPB-FTSS) is a rare genetic disorder characterized by an increased risk of developing pleuropulmonary blastoma (PPB), a type of cancer that affects the lungs and chest wall. People with PPB-FTSS may also be at increased risk of developing other types of cancer, including Wilms tumor, rhabdomyosarcoma, and neuroblastoma. The condition is caused by mutations in the TP53 gene, which is responsible for regulating cell growth and death.