Ocular albinism with late-onset sensorineural deafness is a rare genetic disorder characterized by a lack of pigment in the eyes (ocular albinism) and hearing loss that develops later in life (late-onset sensorineural deafness). It is caused by a mutation in the GPR98 gene, which is responsible for the production of melanin, the pigment that gives color to the eyes and skin. People with this disorder typically have light-colored eyes, pale skin, and white hair. They may also experience vision problems such as nystagmus (involuntary eye movements) and reduced visual acuity. Hearing loss usually begins in the late teens or early twenties and progresses over time.

The symptoms of Ocular albinism with late-onset sensorineural deafness include:

- Reduced vision in one or both eyes
- Nystagmus (involuntary eye movements)
- Strabismus (crossed eyes)
- Photophobia (sensitivity to light)
- Poor depth perception
- Poor night vision
- Poor color vision
- Late-onset sensorineural deafness (hearing loss)

Ocular albinism with late-onset sensorineural deafness is a rare genetic disorder caused by mutations in the GPR143 gene. This gene is responsible for the production of a protein that helps regulate the production of melanin, the pigment that gives color to the eyes and skin. Mutations in this gene can lead to a lack of melanin production, resulting in ocular albinism and late-onset sensorineural deafness.

1. Hearing aids: Hearing aids can help to amplify sound and improve hearing in people with late-onset sensorineural deafness.

2. Cochlear implants: Cochlear implants are surgically implanted devices that can help to improve hearing in people with severe hearing loss.

3. Assistive listening devices: Assistive listening devices, such as FM systems, can help to improve hearing in noisy environments.

4. Speech therapy: Speech therapy can help to improve communication skills in people with late-onset sensorineural deafness.

5. Vision therapy: Vision therapy can help to improve vision in people with ocular albinism. This may include the use of glasses, contact lenses, or vision aids.

1. Genetic predisposition: Ocular albinism with late-onset sensorineural deafness is caused by a genetic mutation in the GPR143 gene.

2. Family history: Individuals with a family history of ocular albinism with late-onset sensorineural deafness are at an increased risk of developing the condition.

3. Age: The condition is more common in individuals over the age of 40.

4. Gender: Males are more likely to be affected than females.

5. Ethnicity: Individuals of African or Asian descent are more likely to be affected than those of European descent.

Unfortunately, there is no cure for ocular albinism with late-onset sensorineural deafness. However, there are medications that can help manage the symptoms associated with the condition. These medications include anticonvulsants, anti-anxiety medications, and antidepressants. Additionally, hearing aids and cochlear implants may be used to help improve hearing.