Non-syndromic unilambdoid craniosynostosis is a type of craniosynostosis, which is a condition in which the bones of the skull fuse together too early. In non-syndromic unilambdoid craniosynostosis, the lambdoid suture, which runs along the back of the skull, fuses prematurely. This can cause the head to become misshapen and can lead to developmental delays and other health problems. Treatment typically involves surgery to reshape the skull and release the fused sutures.

The most common symptoms of non-syndromic unilambdoid craniosynostosis include:

-A misshapen head, with a flat spot on the back of the head
-A wide, slanted forehead
-A prominent ridge along the top of the head
-A flattened area at the back of the head
-A wide, flat area at the back of the head
-A wide, flat area at the sides of the head
-A wide, flat area at the front of the head
-A wide, flat area at the top of the head
-A wide, flat area at the bottom of the head
-A wide, flat area at the sides of the face
-A wide, flat area at the front of the face
-A wide, flat area at the top

Non-syndromic unilambdoid craniosynostosis is a rare condition that is caused by a combination of genetic and environmental factors. Genetic factors include mutations in certain genes that are involved in the development of the skull, such as FGFR2, TWIST1, and MSX2. Environmental factors may include maternal smoking, alcohol consumption, and exposure to certain medications during pregnancy.

1. Surgery: Surgery is the most common treatment for non-syndromic unilambdoid craniosynostosis. The goal of surgery is to reshape the skull and allow for normal brain growth. Surgery is typically performed between 3 and 6 months of age.

2. Cranial Molding Helmets: Cranial molding helmets are used to help reshape the skull and prevent further deformity. The helmet is worn for several months and is adjusted as the skull grows.

3. Physical Therapy: Physical therapy may be recommended to help improve range of motion and strength in the neck and head.

4. Medication: Medication may be prescribed to help reduce swelling and pain.

1. Family history of craniosynostosis
2. Premature birth
3. Low birth weight
4. Exposure to certain medications or drugs during pregnancy
5. Exposure to radiation during pregnancy
6. Maternal diabetes
7. Maternal smoking during pregnancy
8. Maternal alcohol consumption during pregnancy

At this time, there is no cure for non-syndromic unilambdoid craniosynostosis. Treatment typically involves surgery to correct the skull shape and allow for normal brain growth. Medications may be prescribed to help manage pain and discomfort associated with the condition.