Non-syndromic unicoronal craniosynostosis is a type of craniosynostosis, which is a condition in which the bones of the skull fuse together too early. In non-syndromic unicoronal craniosynostosis, only one of the coronal sutures (the sutures that run from ear to ear) fuses prematurely. This can cause the head to become misshapen and can lead to problems with vision, hearing, and brain development. Treatment typically involves surgery to reshape the skull and release the fused suture.

The most common symptoms of non-syndromic unicoronal craniosynostosis include:

-A head shape that is long and narrow
-A prominent forehead
-A flat spot on the top of the head
-A raised ridge along the affected suture
-A wide space between the eyes
-A flattened area on the back of the head
-A flattened area on one side of the head
-A raised ridge along the affected suture
-A wide space between the eyes
-A flattened area on the back of the head
-A flattened area on one side of the head
-A flattened area on the other side of the head
-A flattened area on the forehead
-A flattened area on the back of the head
-A flattened area on the sides of the head
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Non-syndromic unicoronal craniosynostosis is caused by a combination of genetic and environmental factors. Genetic factors include mutations in certain genes, such as FGFR2, TWIST1, and MSX2. Environmental factors include maternal smoking, alcohol consumption, and exposure to certain medications during pregnancy.

1. Surgery: Surgery is the most common treatment for non-syndromic unicoronal craniosynostosis. The goal of surgery is to reshape the skull and allow for normal brain growth. The surgery is usually done in infancy, before the age of 6 months.

2. Physical Therapy: Physical therapy can help improve range of motion and strength in the neck and head. It can also help with balance and coordination.

3. Orthotic Devices: Orthotic devices, such as helmets, can be used to help reshape the skull and protect the head from further deformity.

4. Medication: Medication may be prescribed to help reduce swelling and inflammation.

1. Family history of craniosynostosis
2. Maternal smoking during pregnancy
3. Low birth weight
4. Premature birth
5. Exposure to certain medications during pregnancy
6. Exposure to certain environmental toxins during pregnancy
7. Genetic mutations or chromosomal abnormalities

At this time, there is no cure for non-syndromic unicoronal craniosynostosis. Treatment typically involves surgery to correct the shape of the skull and to allow for normal brain growth. Medications are not typically used to treat this condition.