About Merkel Cell Carcinoma

What is Merkel Cell Carcinoma?

Merkel cell carcinoma (MCC) is a rare and aggressive type of skin cancer. It is a neuroendocrine tumor that usually appears as a firm, painless, flesh-colored or bluish-red nodule on the skin. It is most commonly found on the head, neck, and arms, but can occur anywhere on the body. MCC is caused by a virus called Merkel cell polyomavirus (MCV). Treatment typically involves surgery, radiation, and/or chemotherapy.

What are the symptoms of Merkel Cell Carcinoma?

Common symptoms of Merkel cell carcinoma include:

-A firm, painless, rapidly growing nodule or mass on the skin
-A red, pink, or purple patch of skin
-A sore that does not heal
-Itching or tenderness in the area of the nodule or mass
-Pain in the area of the nodule or mass
-Lymph node swelling near the tumor

What are the causes of Merkel Cell Carcinoma?

The exact cause of Merkel cell carcinoma is unknown, but certain risk factors have been identified. These include:

• Exposure to ultraviolet (UV) radiation from the sun or tanning beds

• Weakened immune system due to HIV/AIDS, organ transplant, or certain medications
• Older age
• Fair skin
• History of other skin cancers
• Exposure to certain viruses, such as the Merkel cell polyomavirus (MCV)
• Exposure to certain chemicals, such as arsenic

What are the treatments for Merkel Cell Carcinoma?

The main treatments for Merkel Cell Carcinoma are surgery, radiation therapy, and chemotherapy. Surgery is the most common treatment and involves removing the tumor and some of the surrounding tissue. Radiation therapy is used to kill any remaining cancer cells and can be used before or after surgery. Chemotherapy is used to kill cancer cells that may have spread to other parts of the body. Immunotherapy is also sometimes used to help the body's immune system fight the cancer.

What are the risk factors for Merkel Cell Carcinoma?

1. Age: Most cases of Merkel cell carcinoma occur in people over the age of 50.

2. Sun exposure: People who have had a lot of sun exposure, especially those with fair skin, are at higher risk for developing Merkel cell carcinoma.

3. Weakened immune system: People with weakened immune systems, such as those with HIV/AIDS or those taking immunosuppressant drugs, are at higher risk for developing Merkel cell carcinoma.

4. History of skin cancer: People who have had other types of skin cancer, such as basal cell carcinoma or squamous cell carcinoma, are at higher risk for developing Merkel cell carcinoma.

5. Exposure to certain viruses: People who have been exposed to certain viruses, such as the Merkel cell polyomavirus, are at higher risk for

Is there a cure/medications for Merkel Cell Carcinoma?

Yes, there are treatments available for Merkel Cell Carcinoma. Treatment options may include surgery, radiation therapy, chemotherapy, immunotherapy, and targeted therapy. Your doctor will discuss the best treatment option for you based on the stage and location of your cancer.