Laryngotracheoesophageal cleft type 0 is a rare congenital disorder in which there is an abnormal opening between the larynx, trachea, and esophagus. This opening can cause food and liquids to enter the airway, leading to aspiration and respiratory problems. Treatment typically involves surgical repair of the cleft and may include speech therapy and other interventions.

Symptoms of Laryngotracheoesophageal cleft type 0 can include:

-Difficulty breathing
-Noisy breathing
-Coughing
-Wheezing
-Choking
-Gagging
-Vomiting
-Feeding difficulties
-Recurrent pneumonia
-Recurrent ear infections
-Hoarseness
-Stridor
-Abnormal chest X-ray findings
-Abnormal swallowing study findings

Laryngotracheoesophageal cleft type 0 is a rare congenital disorder caused by a failure of the larynx, trachea, and esophagus to develop properly during fetal development. The exact cause of this disorder is unknown, but it is believed to be due to a combination of genetic and environmental factors. Possible causes include chromosomal abnormalities, exposure to certain medications or toxins during pregnancy, and maternal infections.

Treatment for laryngotracheoesophageal cleft type 0 typically involves a combination of surgical and medical interventions. Surgical interventions may include closure of the cleft, reconstruction of the larynx and trachea, and repair of any associated anomalies. Medical interventions may include antibiotics to prevent infection, nutritional support, and medications to reduce inflammation and improve airway function. In some cases, a tracheostomy may be necessary to maintain an open airway.

1. Family history of laryngotracheoesophageal cleft
2. Premature birth
3. Low birth weight
4. Exposure to certain medications during pregnancy
5. Genetic syndromes such as CHARGE syndrome, VACTERL association, and DiGeorge syndrome
6. Maternal diabetes
7. Maternal smoking
8. Maternal alcohol use
9. Maternal drug use
10. Maternal obesity

There is no cure for laryngotracheoesophageal cleft type 0, but there are medications that can help manage the symptoms. These medications include antacids, proton pump inhibitors, and prokinetics. Surgery may also be recommended to repair the cleft and improve breathing.