Isolated anencephaly is a rare birth defect in which a baby is born without parts of the brain and skull. It is a fatal condition and most babies with this condition die shortly after birth.

Isolated anencephaly is a fatal condition in which a baby is born without parts of the brain and skull. Symptoms of isolated anencephaly include:

- Absence of the brain and skull
- Absence of the scalp and forehead
- Absence of the eyes
- Absence of the nose
- Absence of the upper jaw
- Absence of the ears
- Absence of the cerebellum
- Absence of the brain stem
- Absence of the thalamus
- Absence of the hypothalamus
- Absence of the pituitary gland
- Absence of the cerebrum
- Absence of the frontal and temporal lobes
- Absence of the occipital lobe
- Absence of the corpus callosum
- Absence of the ventricles

The exact cause of isolated anencephaly is unknown. However, some potential causes may include genetic mutations, environmental factors, and maternal health conditions. Genetic mutations may be inherited from a parent or occur spontaneously. Environmental factors may include exposure to certain toxins or medications during pregnancy. Maternal health conditions such as diabetes, obesity, and certain infections may also increase the risk of anencephaly.

Unfortunately, there is no treatment for isolated anencephaly. The condition is usually diagnosed during pregnancy, and the pregnancy is usually terminated. In some cases, the pregnancy may be allowed to continue, but the baby will not survive after birth.

The risk factors for isolated anencephaly include:

1. Advanced maternal age: Women over the age of 35 are more likely to have a baby with anencephaly.

2. Low maternal folate levels: Women with low levels of folate in their diet are more likely to have a baby with anencephaly.

3. Genetic factors: Certain genetic conditions, such as trisomy 13, can increase the risk of anencephaly.

4. Environmental factors: Exposure to certain environmental toxins, such as pesticides, can increase the risk of anencephaly.

5. Certain medications: Certain medications, such as valproic acid, can increase the risk of anencephaly.

6. Previous pregnancies: Women who have had a previous pregnancy affected by anencephaly are

Unfortunately, there is no cure or medication for isolated anencephaly. Treatment focuses on providing supportive care to the baby and family. This may include providing comfort measures, such as skin-to-skin contact, and helping the family cope with the diagnosis.