Multiple acyl-CoA dehydrogenase deficiency, mild type (MADD-MT) is a rare genetic disorder that affects the body's ability to break down certain fats. It is caused by a deficiency in one or more of the enzymes involved in the breakdown of fatty acids. People with MADD-MT typically have mild symptoms, such as fatigue, muscle weakness, and poor growth. In some cases, the disorder can cause more serious complications, such as seizures, heart problems, and liver failure. Treatment typically involves dietary changes and supplements to help the body break down fats.

The symptoms of Multiple acyl-CoA dehydrogenase deficiency, mild type, can vary from person to person, but may include:

- Poor feeding
- Vomiting
- Lethargy
- Weakness
- Muscle pain
- Muscle cramps
- Exercise intolerance
- Abnormal heart rhythms
- Seizures
- Developmental delay
- Intellectual disability
- Behavioral problems
- Hypoglycemia
- Hyperammonemia
- Elevated liver enzymes

Multiple acyl-CoA dehydrogenase deficiency, mild type is caused by mutations in the ACADM gene. This gene provides instructions for making an enzyme called medium-chain acyl-CoA dehydrogenase (MCAD). This enzyme is involved in breaking down certain fats called medium-chain fatty acids. Mutations in the ACADM gene reduce the activity of MCAD, which can lead to a buildup of medium-chain fatty acids in the body. This can cause the signs and symptoms of multiple acyl-CoA dehydrogenase deficiency, mild type.

The treatment for Multiple acyl-CoA dehydrogenase deficiency, mild type, is primarily dietary management. This includes a low-fat diet, with the majority of fat coming from medium-chain triglycerides (MCTs). MCTs are metabolized differently than other fats, and can provide an alternative source of energy for the body. Additionally, supplements such as carnitine, riboflavin, and coenzyme Q10 may be recommended to help support energy production. In some cases, medications such as valproic acid may be prescribed to help reduce the risk of seizures.

1. Genetic mutation: Multiple acyl-CoA dehydrogenase deficiency, mild type is caused by a genetic mutation in the ACADM gene.

2. Family history: Individuals with a family history of Multiple acyl-CoA dehydrogenase deficiency, mild type are at an increased risk of developing the condition.

3. Ethnicity: Multiple acyl-CoA dehydrogenase deficiency, mild type is more common in individuals of Ashkenazi Jewish descent.

4. Age: Multiple acyl-CoA dehydrogenase deficiency, mild type is more common in infants and young children.

Yes, there is a cure for Multiple acyl-CoA dehydrogenase deficiency, mild type. Treatment typically involves a combination of dietary modifications, medications, and supplements. Dietary modifications may include avoiding certain foods that are high in fat, such as red meat, dairy products, and fried foods. Medications such as carnitine and riboflavin may be prescribed to help the body break down fatty acids. Supplements such as Coenzyme Q10 and omega-3 fatty acids may also be recommended.