Limb-Girdle Muscular Dystrophy (LGMD) is a group of inherited muscle diseases that cause progressive weakness and wasting of the muscles of the hips, shoulders, and upper arms. It is caused by mutations in certain genes that are responsible for producing proteins that are essential for muscle function. Symptoms usually begin in childhood or adolescence and can range from mild to severe. Treatment typically involves physical therapy, occupational therapy, and medications to help manage symptoms.

The symptoms of Limb-Girdle Muscular Dystrophy (LGMD) vary depending on the type of LGMD, but generally include:

- Muscle Weakness and wasting in the hips and shoulders
- Difficulty walking, climbing stairs, and rising from a seated position
- Difficulty lifting objects
- Muscle cramps and spasms
- Joint contractures
- Difficulty breathing
- Cardiac abnormalities
- Fatigue
- Difficulty swallowing

Limb-Girdle Muscular Dystrophy (LGMD) is a group of inherited muscle diseases that cause progressive weakness and wasting of the muscles of the hips, shoulders, and upper arms. The exact cause of LGMD is unknown, but it is believed to be caused by genetic mutations in certain genes. Mutations in these genes can cause the body to produce abnormal proteins that interfere with the normal functioning of the muscles. In some cases, the cause of LGMD is unknown.

1. Physical therapy: Physical therapy can help to maintain muscle strength and flexibility, as well as improve balance and coordination.

2. Occupational therapy: Occupational therapy can help to improve daily living skills, such as dressing, bathing, and eating.

3. Assistive devices: Assistive devices, such as wheelchairs, walkers, and braces, can help to improve mobility and independence.

4. Medications: Certain medications, such as corticosteroids, can help to reduce inflammation and improve muscle strength.

5. Surgery: Surgery may be recommended to correct joint deformities or to improve mobility.

6. Genetic counseling: Genetic counseling can help to provide information about the condition and the risks associated with it.

1. Family history of Limb-Girdle Muscular Dystrophy (LGMD)
2. Certain genetic mutations
3. Age
4. Gender (more common in males)
5. Certain ethnic backgrounds (more common in certain populations)
6. Certain environmental factors (such as exposure to certain toxins)

There is no cure for Limb-Girdle Muscular Dystrophy (LGMD). Treatment focuses on managing symptoms and preventing complications. Medications such as corticosteroids, immunosuppressants, and physical therapy may be used to help manage symptoms. In some cases, surgery may be recommended to correct joint deformities or to help improve mobility.