Kimura disease is a rare inflammatory disorder that affects the lymph nodes, salivary glands, and other tissues in the head and neck area. It is characterized by swelling of the lymph nodes, pain, and tenderness in the neck, and can cause fever, fatigue, and weight loss. It is thought to be an autoimmune disorder, but the exact cause is unknown. Treatment typically involves corticosteroids and other immunosuppressive medications.

The most common symptoms of Kimura disease include:

- Swelling and Pain in the neck, face, and/or jaw
- Swollen lymph nodes in the neck, armpits, and/or groin
- Fever
- Fatigue
- Weight loss
- Night sweats
- Enlarged spleen
- Enlarged liver
- Skin rash
- Abnormal blood tests, including elevated white blood cell count, elevated sedimentation rate, and elevated liver enzymes.

The exact cause of Kimura disease is unknown. However, it is believed to be an autoimmune disorder, meaning that the body's immune system mistakenly attacks healthy cells and tissues. Other possible causes include genetic factors, environmental triggers, and viral or bacterial infections.

The main treatment for Kimura disease is corticosteroid therapy, which is usually administered in the form of oral prednisone. Other treatments may include anti-inflammatory medications, such as non-steroidal anti-inflammatory drugs (NSAIDs), immunosuppressants, and biologic agents. Surgery may also be recommended in some cases to remove the affected lymph nodes.

1. Age: Kimura disease is most commonly seen in young adults, typically between the ages of 20 and 40.

2. Gender: Kimura disease is more common in males than females.

3. Ethnicity: Kimura disease is more common in people of Asian descent.

4. Genetics: Kimura disease is believed to have a genetic component, as it is more common in people with a family history of the disease.

5. Environment: Exposure to certain environmental factors, such as certain chemicals, may increase the risk of developing Kimura disease.

There is no known cure for Kimura disease. Treatment typically involves medications to reduce inflammation and pain, such as corticosteroids, nonsteroidal anti-inflammatory drugs (NSAIDs), and immunosuppressants. Surgery may be recommended in some cases to remove the affected lymph nodes.