Isolated female hypospadias is a rare congenital disorder in which the urethral opening of a female is located on the underside of the clitoris instead of at the normal location at the tip of the clitoris. It is a form of hypospadias, a condition in which the urethral opening is abnormally located on the underside of the penis in males.

The most common symptoms of isolated female hypospadias include:

-A urethral opening located anywhere along the underside of the clitoris, instead of at the tip
-A hooded clitoris, which is a clitoris that is partially or completely covered by a fold of skin
-A labia minora that is fused together
-A shallow vaginal opening
-A curved or bent urinary stream
-Difficulty with urination, such as dribbling or spraying of urine
-Recurrent urinary tract infections
-Painful urination or difficulty with urination

Isolated female hypospadias is a rare condition that is caused by a combination of genetic and environmental factors. The exact cause is unknown, but it is believed to be related to a combination of genetic and environmental factors, such as exposure to certain hormones or chemicals during pregnancy. Other possible causes include chromosomal abnormalities, maternal diabetes, and maternal smoking.

1. Surgery: Surgery is the most common treatment for isolated female hypospadias. The goal of the surgery is to reconstruct the urethra and create a normal opening in the correct location.

2. Hormone Therapy: Hormone therapy may be used to help the urethra develop in the correct location.

3. Skin Grafts: Skin grafts may be used to help reconstruct the urethra and create a normal opening.

4. Urethral Dilatation: Urethral dilatation may be used to help widen the urethra and create a normal opening.

5. Urethral Stent: A urethral stent may be used to help keep the urethra open and allow for normal urine flow.

1. Advanced maternal age
2. Maternal diabetes
3. Maternal obesity
4. Maternal smoking
5. Maternal use of certain medications, such as anticonvulsants
6. Maternal exposure to certain environmental toxins, such as phthalates
7. Family history of hypospadias
8. Low birth weight
9. Prematurity
10. Male sex of the baby

There is no cure for isolated female hypospadias, but there are treatments available to help improve the appearance and function of the affected area. Treatment options may include reconstructive surgery, hormone therapy, and topical medications. The type of treatment recommended will depend on the severity of the condition and the individual patient's needs.