Isolated agenesis of gallbladder is a rare congenital disorder in which the gallbladder is absent from the body. It is usually asymptomatic and is often discovered incidentally during imaging tests. Treatment is not usually necessary, but if symptoms develop, medications may be prescribed to help manage them.

The most common symptom of isolated agenesis of the gallbladder is abdominal pain. Other symptoms may include nausea, vomiting, indigestion, bloating, and diarrhea. In some cases, patients may also experience jaundice, fever, and weight loss.

Isolated agenesis of the gallbladder is a rare congenital anomaly that is believed to be caused by a combination of genetic and environmental factors. Genetic factors may include mutations in certain genes, such as the PAX2 gene, which is involved in the development of the gallbladder. Environmental factors may include exposure to certain toxins or medications during pregnancy.

The treatment for isolated agenesis of the gallbladder is typically not necessary, as it is usually asymptomatic and does not cause any health problems. However, if the condition is causing symptoms, such as abdominal pain, nausea, or vomiting, then medications such as antispasmodics, antacids, and proton pump inhibitors may be prescribed to help relieve the symptoms. In some cases, surgery may be recommended to remove any stones that may have formed in the bile ducts.

1. Family history of gallbladder agenesis
2. Female gender
3. Obesity
4. Diabetes
5. Hypertension
6. Smoking
7. High cholesterol
8. Age over 40

There is no cure for isolated agenesis of the gallbladder. Treatment typically involves managing symptoms with medications such as antacids, proton pump inhibitors, and antibiotics. Surgery may be recommended in some cases to remove any stones that may have formed in the bile ducts.