Intralobar congenital pulmonary sequestration is a rare congenital malformation in which a portion of the lung is not connected to the normal airways and is supplied by its own blood supply. It is usually located in the lower lobes of the lungs and is often associated with other congenital anomalies. Symptoms may include recurrent pneumonia, chest pain, and difficulty breathing. Treatment typically involves surgical removal of the affected lobe.

The most common symptoms of Intralobar Congenital Pulmonary Sequestration are:

-Persistent cough
-Wheezing
-Shortness of breath
-Recurrent chest infections
-Fever
-Rapid breathing
-Abdominal pain
-Failure to thrive
-Cyanosis (bluish discoloration of the skin)
-Clubbing of the fingers and toes

The exact cause of intralobar congenital pulmonary sequestration is unknown. It is thought to be caused by abnormal development of the fetal lungs during the early stages of pregnancy. It is believed that the abnormal development of the fetal lungs is due to a combination of genetic and environmental factors.

The primary treatment for intralobar congenital pulmonary sequestration is surgical resection. This involves removing the sequestered lobe of the lung, as well as any associated blood vessels. In some cases, a portion of the normal lung may also need to be removed. In some cases, a minimally invasive approach may be used, such as video-assisted thoracoscopic surgery (VATS). In some cases, a combination of surgery and chemotherapy may be used. In some cases, radiation therapy may be used to shrink the sequestered lobe before surgery.

1. Intralobar sequestration is more common in males than females.
2. It is more common in premature infants.
3. It is more common in individuals with a family history of congenital pulmonary sequestration.
4. It is more common in individuals with other congenital anomalies, such as congenital heart defects.
5. It is more common in individuals with chromosomal abnormalities, such as Down syndrome.
6. It is more common in individuals with certain genetic syndromes, such as Turner syndrome.

There is no cure for intralobar congenital pulmonary sequestration, but medications can be used to manage symptoms. These medications may include antibiotics to treat infections, bronchodilators to open the airways, and anti-inflammatory medications to reduce inflammation. Surgery may also be recommended to remove the affected lobe of the lung.