About Idiopathic steroid-sensitive nephrotic syndrome

What is Idiopathic steroid-sensitive nephrotic syndrome?

Idiopathic steroid-sensitive nephrotic syndrome (ISNS) is a type of kidney disease that affects children. It is characterized by the presence of protein in the urine (proteinuria), swelling (edema), and low levels of protein in the blood (hypoalbuminemia). ISNS is usually treated with corticosteroids, which can help reduce the amount of protein in the urine and improve kidney function.

What are the symptoms of Idiopathic steroid-sensitive nephrotic syndrome?

The most common symptoms of Idiopathic steroid-sensitive nephrotic syndrome are:

-Swelling of the face, hands, feet, and abdomen
-High levels of protein in the urine
-Foamy urine
-High levels of cholesterol in the blood
-Fatigue
-Weight gain
-Loss of appetite
-Nausea
-Vomiting
-Itching
-High blood pressure

What are the causes of Idiopathic steroid-sensitive nephrotic syndrome?

The exact cause of idiopathic steroid-sensitive nephrotic syndrome is unknown. However, it is believed to be an autoimmune disorder, meaning that the body's immune system mistakenly attacks its own healthy cells and tissues. Other possible causes include genetic factors, environmental triggers, and infections.

What are the treatments for Idiopathic steroid-sensitive nephrotic syndrome?

The main treatment for idiopathic steroid-sensitive nephrotic syndrome is corticosteroids, such as prednisone. Other treatments may include:

• ACE inhibitors or angiotensin receptor blockers (ARBs) to reduce blood pressure and protect the kidneys

• Diuretics to reduce fluid retention

• Immunosuppressants, such as cyclosporine or tacrolimus, to reduce inflammation

• Antibiotics to treat any infections

• Low-salt diet to reduce fluid retention

• Low-protein diet to reduce the amount of waste products in the blood

• Vitamin D supplements to help maintain healthy bones

• Iron supplements to treat anemia

• Regular monitoring of blood pressure, urine, and blood tests to check kidney function

What are the risk factors for Idiopathic steroid-sensitive nephrotic syndrome?

1. Age: Idiopathic steroid-sensitive nephrotic syndrome is most common in children between the ages of 2 and 6.

2. Gender: Boys are more likely to develop this condition than girls.

3. Ethnicity: African-American and Asian children are more likely to develop this condition than Caucasian children.

4. Family history: Having a family member with the condition increases the risk of developing it.

5. Infections: Certain viral and bacterial infections can increase the risk of developing this condition.

Is there a cure/medications for Idiopathic steroid-sensitive nephrotic syndrome?

Yes, there are medications available to treat idiopathic steroid-sensitive nephrotic syndrome. These medications include corticosteroids, such as prednisone, and immunosuppressants, such as cyclosporine and tacrolimus. Additionally, other medications, such as angiotensin-converting enzyme (ACE) inhibitors, angiotensin receptor blockers (ARBs), and diuretics, may be prescribed to help manage symptoms.