About Iatrogenic Creutzfeldt-Jakob disease

What is Iatrogenic Creutzfeldt-Jakob disease?

Iatrogenic Creutzfeldt-Jakob disease (iCJD) is a rare and fatal neurological disorder caused by the transmission of the abnormal prion protein that causes Creutzfeldt-Jakob disease (CJD). It is caused by medical procedures that involve the transfer of contaminated tissue or medical instruments from an infected individual to a healthy individual. It is a rare form of CJD, accounting for only about 1% of all cases. Symptoms of iCJD are similar to those of other forms of CJD, including rapidly progressive dementia, involuntary muscle jerks, and visual disturbances. There is no cure for iCJD and it is always fatal.

What are the symptoms of Iatrogenic Creutzfeldt-Jakob disease?

Symptoms of Iatrogenic Creutzfeldt-Jakob disease (iCJD) can vary depending on the individual, but generally include:

- Rapidly progressive dementia

- Memory loss

- Visual disturbances

- Difficulty speaking and understanding language

- Unsteady gait

- Muscle twitches and jerks

- Myoclonus (involuntary muscle contractions)

- Loss of coordination

- Personality changes

- Depression

- Anxiety

- Insomnia

- Seizures

What are the causes of Iatrogenic Creutzfeldt-Jakob disease?

Iatrogenic Creutzfeldt-Jakob disease (iCJD) is caused by exposure to contaminated medical instruments or tissue, such as those used in brain surgery, corneal transplants, or dura mater grafts. It can also be caused by the injection of contaminated human growth hormone or the use of contaminated electrodes during electroconvulsive therapy.

What are the treatments for Iatrogenic Creutzfeldt-Jakob disease?

Unfortunately, there is no known cure for Iatrogenic Creutzfeldt-Jakob disease (iCJD). Treatment is focused on managing symptoms and providing supportive care. This may include medications to help with sleep, pain, and anxiety, as well as physical and occupational therapy to help maintain mobility and independence. Additionally, families may benefit from counseling and support services to help cope with the diagnosis.

What are the risk factors for Iatrogenic Creutzfeldt-Jakob disease?

1. Receiving a contaminated human growth hormone injection
2. Receiving a contaminated dura mater graft
3. Receiving a contaminated corneal transplant
4. Receiving a contaminated human pituitary hormone
5. Receiving a contaminated human gonadotropin
6. Receiving a contaminated human gonadotropin-releasing hormone
7. Receiving a contaminated human insulin
8. Receiving a contaminated human albumin
9. Receiving a contaminated human immunoglobulin
10. Receiving a contaminated human fibrinogen
11. Receiving a contaminated human thrombin
12. Receiving a contaminated human factor VIII
13. Receiving a contaminated human factor IX
14. Receiving a contaminated human factor XI
15. Receiving a contaminated human factor XIII
16. Receiving a contaminated human

Is there a cure/medications for Iatrogenic Creutzfeldt-Jakob disease?

Unfortunately, there is no cure or medication for Iatrogenic Creutzfeldt-Jakob disease. Treatment is focused on providing supportive care to manage symptoms and improve quality of life. This may include medications to manage pain, seizures, and other symptoms, as well as physical, occupational, and speech therapy.