About Hypertrichosis lanuginosa congenita

What is Hypertrichosis lanuginosa congenita?

Hypertrichosis lanuginosa congenita is a rare genetic disorder characterized by excessive hair growth on the face and body. It is caused by a mutation in the gene that controls hair growth. Symptoms usually appear at birth or in early childhood and can include thick, long, and curly hair on the face, neck, chest, back, arms, and legs. The hair may be lighter in color than the rest of the body hair. In some cases, the hair may be so thick that it covers the eyes, nose, and mouth.

What are the symptoms of Hypertrichosis lanuginosa congenita?

The symptoms of Hypertrichosis lanuginosa congenita include excessive hair growth on the face, scalp, and body, thick eyebrows, long eyelashes, and thick scalp hair. Other symptoms may include a wide nasal bridge, a prominent forehead, and a pointed chin. In some cases, the hair may be so thick that it covers the eyes, ears, and mouth.

What are the causes of Hypertrichosis lanuginosa congenita?

Hypertrichosis lanuginosa congenita is a rare genetic disorder caused by mutations in the KRT25 gene. This gene is responsible for the production of a protein called keratin 25, which is essential for the normal development of hair follicles. Mutations in this gene can lead to an overproduction of hair, resulting in the excessive hair growth seen in Hypertrichosis lanuginosa congenita.

What are the treatments for Hypertrichosis lanuginosa congenita?

The primary treatment for Hypertrichosis lanuginosa congenita is laser hair removal. This is a safe and effective way to reduce the amount of excess hair growth. Other treatments may include topical medications, such as minoxidil, to reduce hair growth, and electrolysis to permanently remove hair. In some cases, surgery may be recommended to remove the excess hair.

What are the risk factors for Hypertrichosis lanuginosa congenita?

1. Genetic mutations in the GATA2 gene
2. Family history of the condition
3. Exposure to certain medications or chemicals during pregnancy
4. Exposure to radiation during pregnancy
5. Maternal diabetes or obesity during pregnancy
6. Premature birth or low birth weight

Is there a cure/medications for Hypertrichosis lanuginosa congenita?

At this time, there is no known cure for Hypertrichosis lanuginosa congenita. However, there are medications that can be used to help manage the symptoms. These include topical corticosteroids, topical retinoids, and laser hair removal. Additionally, there are some lifestyle changes that can help reduce the symptoms, such as avoiding excessive sun exposure and using sunscreen.