Haberland Syndrome, also known as Encephalocraniocutaneous Lipomatosis, is a rare genetic disorder characterized by the presence of benign fatty tumors (lipomas) on the scalp, face, and neck. It is also associated with neurological abnormalities, including seizures, developmental delays, and intellectual disability. The cause of Haberland Syndrome is unknown, but it is believed to be inherited in an autosomal recessive pattern.

The symptoms of Haberland Syndrome (Encephalocraniocutaneous Lipomatosis) include:

-Facial abnormalities, including a wide forehead, low-set ears, and a small jaw
-Soft, fatty tumors on the scalp, face, and neck
-Developmental delays
-Seizures
-Intellectual disability
-Vision and hearing problems
-Feeding difficulties
-Abnormalities of the hands and feet
-Abnormalities of the spine
-Abnormalities of the heart and other organs

Haberland Syndrome (Encephalocraniocutaneous Lipomatosis) is a rare genetic disorder caused by a mutation in the PIK3CA gene. This gene is responsible for the production of a protein called phosphatidylinositol 3-kinase (PI3K). This protein is involved in the regulation of cell growth and development. Mutations in this gene can lead to the abnormal growth of fat cells in the brain, skin, and other parts of the body. This can cause a variety of symptoms, including seizures, developmental delays, and facial abnormalities.

The treatments for Haberland Syndrome (Encephalocraniocutaneous Lipomatosis) vary depending on the severity of the condition. Generally, the main treatment is surgical removal of the lipomas, which can be done through a variety of techniques. Other treatments may include physical therapy, speech therapy, occupational therapy, and medications to help manage seizures and other neurological symptoms. In some cases, reconstructive surgery may be necessary to improve facial appearance.

1. Genetic mutation in the PIK3CA gene
2. Family history of the disorder
3. Maternal exposure to certain medications during pregnancy
4. Maternal diabetes
5. Maternal obesity
6. Maternal smoking
7. Maternal alcohol consumption
8. Maternal age over 35 years

At this time, there is no known cure for Haberland Syndrome (Encephalocraniocutaneous Lipomatosis). Treatment is focused on managing the symptoms and complications associated with the condition. This may include medications to control seizures, physical therapy to help with motor skills, and surgery to remove any tumors or lipomas that may be causing problems.