GMS syndrome, also known as GMS-Syndrome, is a rare genetic disorder characterized by a combination of physical and mental disabilities. It is caused by a mutation in the GMS1 gene, which is responsible for the production of a protein called GMS1. Symptoms of GMS syndrome include intellectual disability, seizures, hypotonia, facial dysmorphism, and skeletal abnormalities.

The symptoms of GMS syndrome vary from person to person, but may include:

-Developmental delays
-Intellectual disability
-Seizures
-Growth delays
-Feeding difficulties
-Hearing loss
-Vision problems
-Heart defects
-Kidney problems
-Gastrointestinal issues
-Skin abnormalities
-Muscle weakness
-Joint problems
-Behavioral issues

GMS syndrome is a rare genetic disorder caused by a mutation in the GMS gene. The mutation affects the production of a protein called GMS, which is involved in the development of the brain and nervous system. The exact cause of the mutation is unknown, but it is believed to be inherited in an autosomal recessive pattern.

The primary treatment for GMS syndrome is physical therapy. Physical therapy can help improve strength, flexibility, and coordination. Other treatments may include occupational therapy, speech therapy, and medications to help manage symptoms. Surgery may be recommended in some cases to correct physical deformities or to improve mobility.

1. Advanced maternal age
2. Family history of GMS syndrome
3. Maternal diabetes
4. Maternal obesity
5. Maternal smoking
6. Maternal alcohol consumption
7. Maternal drug use
8. Maternal exposure to certain environmental toxins
9. Maternal infection
10. Maternal nutritional deficiencies

At this time, there is no known cure for GMS syndrome. However, there are medications that can help manage the symptoms of GMS syndrome. These medications include anticonvulsants, muscle relaxants, and antidepressants. Additionally, physical therapy and occupational therapy can help improve muscle strength and coordination.