Gingival fibromatosis-facial dysmorphism syndrome is a rare genetic disorder characterized by excessive growth of the gums (gingival fibromatosis) and facial abnormalities. The facial abnormalities may include a wide mouth, a prominent chin, and a wide nose. Other features may include a cleft palate, a high-arched palate, and/or a small lower jaw. The gingival fibromatosis can cause the teeth to be crowded and the gums to be thick and overgrown. This can lead to difficulty in brushing and flossing, which can lead to an increased risk of tooth decay and gum disease. Treatment may include surgery to reduce the size of the gums and orthodontic treatment to correct the alignment of the teeth.

The symptoms of Gingival Fibromatosis-Facial Dysmorphism Syndrome (GFD) include:

1. Abnormally large and thick gums (gingival hyperplasia)

2. Abnormal facial features, including a wide mouth, a long face, and a prominent chin

3. Delayed tooth eruption

4. Abnormal tooth shape and size

5. Abnormal tooth alignment

6. Abnormal jaw growth

7. Abnormal speech

8. Abnormal swallowing

9. Abnormal breathing

10. Abnormal facial expressions

11. Abnormal muscle tone

12. Abnormal joint mobility

13. Abnormal posture

14. Abnormal gait

15. Abnormal behavior

16. Abnormal sleep patterns

Gingival fibromatosis-facial dysmorphism syndrome is a rare genetic disorder caused by mutations in the FGF3 gene. This gene is responsible for producing a protein that helps regulate the growth of cells in the gums and other parts of the body. Mutations in this gene can cause abnormal growth of the gums, leading to the symptoms of the syndrome.

1. Regular dental check-ups and professional cleanings to remove plaque and tartar buildup.

2. Surgery to remove excess gum tissue and reshape the gums.

3. Orthodontic treatment to correct any misalignment of the teeth.

4. Medications to reduce inflammation and pain.

5. Laser therapy to reduce the size of the gums.

6. Speech therapy to help with any speech difficulties caused by the condition.

7. Psychological counseling to help with any emotional issues related to the condition.

1. Genetic predisposition: Gingival fibromatosis-facial dysmorphism syndrome is an inherited disorder caused by a mutation in the gene encoding the protein fibroblast growth factor receptor 3 (FGFR3).

2. Environmental factors: Exposure to certain environmental factors, such as smoking, poor oral hygiene, and certain medications, may increase the risk of developing gingival fibromatosis-facial dysmorphism syndrome.

3. Age: The condition is more common in children and adolescents.

Unfortunately, there is no known cure for Gingival Fibromatosis-Facial Dysmorphism Syndrome. However, there are medications that can help manage the symptoms. These include anti-inflammatory medications, antibiotics, and antifungal medications. Additionally, surgery may be recommended to reduce the size of the gums and improve the appearance of the face.