Genetic non-syndromic obesity is a type of obesity that is caused by genetic factors and is not associated with any other medical condition or syndrome. It is caused by mutations in certain genes that affect the body's ability to regulate appetite and metabolism. These mutations can lead to an increased risk of obesity, even when a person has a healthy diet and exercise routine.

Symptoms of genetic non-syndromic obesity include:

-Excessive weight gain
-Difficulty losing weight
-Increased appetite
-Cravings for high-calorie foods
-Lack of energy
-Low self-esteem
-Depression
-Sleep apnea
-High blood pressure
-High cholesterol
-Type 2 diabetes
-Joint pain
-Gallbladder disease
-Heart disease

1. Genetic mutations: Certain genetic mutations can cause obesity. These mutations can affect the way the body processes and stores fat, or how it responds to hormones that regulate appetite.

2. Family history: Obesity can run in families, suggesting that genetic factors may play a role.

3. Environment: Environmental factors, such as a person’s diet and activity level, can also contribute to obesity.

4. Medications: Certain medications, such as steroids, can cause weight gain.

5. Medical conditions: Certain medical conditions, such as hypothyroidism, can lead to obesity.

1. Diet and Exercise: A healthy diet and regular exercise are the most important treatments for genetic non-syndromic obesity. Eating a balanced diet and exercising regularly can help to reduce weight and improve overall health.

2. Medications: Certain medications, such as orlistat, lorcaserin, and phentermine-topiramate, can help to reduce weight in people with genetic non-syndromic obesity.

3. Surgery: Bariatric surgery, such as gastric bypass or sleeve gastrectomy, can be an effective treatment for people with severe obesity.

4. Lifestyle Changes: Making lifestyle changes, such as reducing stress, getting enough sleep, and avoiding triggers for overeating, can help to reduce weight and improve overall health.

1. Family history of obesity
2. Low physical activity
3. High-calorie diet
4. Certain medications
5. Endocrine disorders
6. Sleep deprivation
7. Age
8. Gender
9. Ethnicity
10. Socioeconomic status

There is no cure for genetic non-syndromic obesity, but there are medications that can help manage the condition. These medications work by suppressing appetite, increasing metabolism, or blocking the absorption of fat. However, these medications should only be used in conjunction with lifestyle changes such as diet and exercise.