About Gelatinous drop-like corneal dystrophy

What is Gelatinous drop-like corneal dystrophy?

Gelatinous drop-like corneal dystrophy (GDLD) is a rare, inherited eye disorder that affects the cornea, the clear outer layer of the eye. It is characterized by the accumulation of a gelatinous material in the cornea, which can cause vision problems. Symptoms of GDLD include blurred vision, sensitivity to light, and a decrease in vision over time. Treatment for GDLD typically involves the use of eye drops or surgery to remove the gelatinous material.

What are the symptoms of Gelatinous drop-like corneal dystrophy?

The most common symptoms of Gelatinous Drop-like Corneal Dystrophy (GDLD) include:

-Blurred vision

-Sensitivity to light

-Halos around lights

-Decreased vision

-Pain or discomfort in the eyes

-A feeling of something in the eye

-A grayish-white, gelatinous material in the cornea that can be seen with a slit lamp examination

What are the causes of Gelatinous drop-like corneal dystrophy?

Gelatinous drop-like corneal dystrophy is caused by a mutation in the CHST6 gene. This gene is responsible for producing an enzyme called chondroitin-6-sulfotransferase, which is involved in the production of a protein called keratan sulfate. When this enzyme is not produced correctly, it can lead to the accumulation of abnormal proteins in the cornea, resulting in the formation of the characteristic gelatinous drops.

What are the treatments for Gelatinous drop-like corneal dystrophy?

1. Corneal transplantation: This is the most effective treatment for Gelatinous drop-like corneal dystrophy. It involves replacing the affected corneal tissue with healthy donor tissue.

2. Phototherapeutic keratectomy (PTK): This procedure uses a laser to remove the abnormal cells from the cornea.

3. Corneal collagen cross-linking: This procedure strengthens the cornea by increasing the number of collagen fibers in the cornea.

4. Intacs: This procedure involves inserting tiny plastic rings into the cornea to flatten it and improve vision.

5. Corneal implants: This procedure involves implanting a synthetic material into the cornea to improve vision.

6. Corneal inlays: This procedure involves implanting a small device

What are the risk factors for Gelatinous drop-like corneal dystrophy?

1. Genetic predisposition: Gelatinous drop-like corneal dystrophy is an inherited disorder caused by mutations in the CHST6 gene.

2. Age: The condition usually appears in childhood or adolescence, but can also occur in adulthood.

3. Gender: The condition is more common in females than males.

4. Ethnicity: Gelatinous drop-like corneal dystrophy is more common in people of Asian descent.

Is there a cure/medications for Gelatinous drop-like corneal dystrophy?

There is no known cure for gelatinous drop-like corneal dystrophy. However, there are medications that can help manage the symptoms. These include topical lubricants, such as artificial tears, to reduce dryness and discomfort, and topical steroids to reduce inflammation. In some cases, surgery may be recommended to improve vision.