Fibular dimelia-diplopodia syndrome is a rare genetic disorder characterized by the presence of two fibulae (lower leg bones) and two feet (diplopodia). It is caused by a mutation in the HOXD13 gene, which is responsible for the development of the lower limbs. Symptoms of the disorder include short stature, joint contractures, and skeletal abnormalities. Treatment typically involves physical therapy, orthopedic surgery, and bracing.

The symptoms of Fibular dimelia-diplopodia syndrome include:

-Short stature
-Underdeveloped fibula bones
-Abnormal development of the feet, including extra toes, webbing between toes, and/or fused toes
-Abnormal development of the hands, including extra fingers, webbing between fingers, and/or fused fingers
-Abnormal development of the skull, including a Small head and/or a flattened back of the head
-Abnormal development of the face, including a small jaw and/or a wide-set eyes
-Abnormal development of the spine, including Scoliosis and/or kyphosis
-Abnormal development of the hips, including hip dysplasia and/or dislocation
-Abnormal development of the kidneys, including cysts and/or malformations

Fibular dimelia-diplopodia syndrome is a rare genetic disorder caused by a mutation in the HOXD13 gene. This gene is responsible for the development of the lower limbs, and when it is mutated, it can cause the abnormal development of the fibula, resulting in the syndrome. Other causes of the syndrome include chromosomal abnormalities, such as trisomy 18, and environmental factors, such as exposure to certain toxins or radiation.

There is no known cure for Fibular dimelia-diplopodia syndrome. Treatment focuses on managing the symptoms and complications associated with the condition. This may include physical therapy, orthopedic surgery, and the use of assistive devices such as braces, splints, and crutches. In some cases, medications may be prescribed to help manage pain and other symptoms.

1. Genetic mutation: Fibular dimelia-diplopodia syndrome is caused by a mutation in the HOXD13 gene.

2. Family history: Individuals with a family history of the disorder are at an increased risk of developing the condition.

3. Gender: Fibular dimelia-diplopodia syndrome is more common in males than females.

4. Ethnicity: The disorder is more common in individuals of African descent.

Unfortunately, there is no known cure or medications for Fibular dimelia-diplopodia syndrome. Treatment is focused on managing the symptoms and complications associated with the condition. This may include physical therapy, orthopedic surgery, and other supportive measures.