Familial short QT syndrome (SQTS) is a rare genetic disorder that affects the electrical activity of the heart. It is characterized by a shortened QT interval on an electrocardiogram (ECG), which is a measure of the time it takes for the heart to recharge between beats. People with SQTS are at an increased risk of developing life-threatening arrhythmias, such as ventricular tachycardia and ventricular fibrillation. Treatment typically involves medications to control the heart rate and rhythm, as well as lifestyle modifications.

The most common symptoms of Familial Short QT Syndrome (FSQTS) include:

-Palpitations
-Lightheadedness
-Fainting
-Seizures
-Sudden cardiac death
-Abnormal heart rhythms (arrhythmias)
-Shortened QT interval on an electrocardiogram (ECG)
-Abnormal heart structure (such as an enlarged left ventricle)
-Family history of sudden cardiac death or arrhythmias

Familial short QT syndrome is caused by mutations in genes that are responsible for controlling the electrical activity of the heart. These mutations can cause the heart to beat too quickly and can lead to an increased risk of sudden cardiac death.

The main treatment for Familial Short QT Syndrome is the use of medications to reduce the risk of sudden cardiac death. These medications include beta-blockers, calcium channel blockers, and potassium channel blockers. Implantable cardioverter defibrillators (ICDs) may also be recommended for those at high risk of sudden cardiac death. In some cases, a pacemaker may be recommended to help regulate the heart rate. Genetic counseling may also be recommended for those with a family history of the condition.

The primary risk factor for Familial short QT syndrome is a family history of the condition. Other risk factors include a history of sudden cardiac death in a family member, a history of arrhythmias, and a history of syncope.

At this time, there is no cure for Familial Short QT Syndrome (FSQTS). However, medications such as beta-blockers, calcium channel blockers, and potassium channel blockers may be used to help manage the symptoms of FSQTS. Additionally, lifestyle modifications such as avoiding strenuous physical activity and avoiding certain medications can help reduce the risk of arrhythmias associated with FSQTS.