About Extramammary Paget disease

What is Extramammary Paget disease?

Extramammary Paget disease (EMPD) is a rare form of skin cancer that affects the external genitalia, perianal area, and other skin areas outside of the breast. It is caused by the abnormal growth of cells in the epidermis, the outermost layer of the skin. Symptoms of EMPD include itching, burning, and redness in the affected area. Treatment typically involves surgery to remove the affected skin, followed by radiation therapy or chemotherapy.

What are the symptoms of Extramammary Paget disease?

The most common symptom of Extramammary Paget disease is an itchy, scaly, red rash that may appear on the skin of the genitals, inner thighs, or buttocks. Other symptoms may include:

- Burning or stinging sensation

- Skin thickening

- Skin discoloration

- Discharge from the affected area

- Pain or tenderness

- Swelling

- Itching

- Skin Lesions or bumps

What are the causes of Extramammary Paget disease?

The exact cause of Extramammary Paget disease is unknown. However, it is believed to be related to an underlying skin disorder, such as an infection, an allergic reaction, or an autoimmune disorder. Other possible causes include genetic factors, environmental factors, and exposure to certain chemicals.

What are the treatments for Extramammary Paget disease?

The main treatment for Extramammary Paget disease is surgical excision. This involves removing the affected area of skin and some of the surrounding tissue. Other treatments may include topical chemotherapy, radiation therapy, and cryotherapy. In some cases, a combination of treatments may be used.

What are the risk factors for Extramammary Paget disease?

1. Age: Most cases of Extramammary Paget disease occur in people over the age of 50.

2. Gender: Men are more likely to develop Extramammary Paget disease than women.

3. Genetics: People with a family history of Extramammary Paget disease may be at an increased risk of developing the condition.

4. Personal hygiene: Poor hygiene may increase the risk of developing Extramammary Paget disease.

5. Exposure to irritants: Exposure to certain irritants, such as soaps, detergents, and other chemicals, may increase the risk of developing Extramammary Paget disease.

Is there a cure/medications for Extramammary Paget disease?

Yes, there are treatments available for Extramammary Paget disease. Treatment options include topical medications, such as imiquimod cream, and surgical removal of the affected area. In some cases, radiation therapy may also be used. Your doctor will be able to discuss the best treatment option for you.