About Exercise-induced malignant hyperthermia

What is Exercise-induced malignant hyperthermia?

Exercise-induced malignant hyperthermia (EIMH) is a rare, inherited disorder that can cause a sudden, life-threatening rise in body temperature during or after exercise. It is caused by a genetic mutation in the ryanodine receptor, which is responsible for controlling the release of calcium from the muscle cells. Symptoms of EIMH include muscle rigidity, rapid heart rate, and elevated body temperature. Treatment typically involves cooling the body and administering dantrolene, a medication that helps to reduce muscle contractions.

What are the symptoms of Exercise-induced malignant hyperthermia?

Symptoms of Exercise-induced malignant hyperthermia include:

-Rapid heart rate
-High body temperature
-Muscle rigidity
-Excessive sweating
-Rapid breathing
-Confusion
-Lightheadedness
-Nausea
-Vomiting
-Abdominal pain
-Diarrhea
-Seizures

What are the causes of Exercise-induced malignant hyperthermia?

Exercise-induced malignant hyperthermia (EIMH) is a rare, inherited disorder that is triggered by strenuous physical activity. It is caused by a genetic mutation in the ryanodine receptor (RYR1) gene, which is responsible for controlling the release of calcium from the muscle cells. This mutation causes an abnormal release of calcium, leading to an increase in body temperature, muscle rigidity, and other symptoms. Other causes of EIMH include certain medications, such as halothane and succinylcholine, and certain environmental triggers, such as high temperatures and humidity.

What are the treatments for Exercise-induced malignant hyperthermia?

1. Discontinue the exercise or activity that triggered the malignant hyperthermia.
2. Administer dantrolene sodium, a medication that helps relax the muscles and reduce the body temperature.
3. Provide supportive care, such as intravenous fluids and oxygen, to help stabilize the patient.
4. Monitor the patient’s vital signs and electrolyte levels.
5. Administer cooling measures, such as cooling blankets or ice packs, to reduce the body temperature.
6. Monitor the patient for any signs of complications, such as cardiac arrhythmias or respiratory distress.

What are the risk factors for Exercise-induced malignant hyperthermia?

1. Family history of EIMH
2. Certain genetic mutations
3. Certain medications
4. Certain medical conditions, such as muscular dystrophy
5. Certain environmental factors, such as high temperatures or humidity
6. Certain types of exercise, such as high-intensity interval training or weightlifting

Is there a cure/medications for Exercise-induced malignant hyperthermia?

Exercise-induced malignant hyperthermia is a rare condition that is caused by a genetic mutation. There is no cure for this condition, but medications can be used to help manage the symptoms. These medications include dantrolene, which helps to relax the muscles, and beta-blockers, which can help to reduce the risk of a malignant hyperthermia episode. Additionally, avoiding strenuous exercise and staying cool can help to reduce the risk of an episode.