Endometrial stromal sarcoma (ESS) is a rare type of cancer that develops in the endometrium, the lining of the uterus. It is a type of sarcoma, which is a cancer that develops in the connective tissues of the body. Symptoms of ESS may include abnormal vaginal bleeding, pelvic pain, and a mass in the uterus. Treatment for ESS may include surgery, radiation therapy, and chemotherapy.

The most common symptom of endometrial stromal sarComa is abnormal vaginal bleeding. Other symptoms may include pelvic pain, Pain during intercourse, and a feeling of fullness in the lower abdomen.

The exact cause of endometrial stromal sarcoma is unknown. However, some risk factors have been identified, including:

• Age: Endometrial stromal sarcoma is more common in women over the age of 50.

• Obesity: Women who are obese are more likely to develop endometrial stromal sarcoma.

• Estrogen exposure: Women who have been exposed to high levels of estrogen, either through hormone replacement therapy or through certain types of birth control, may be at an increased risk of developing endometrial stromal sarcoma.

• Genetic mutations: Certain genetic mutations, such as those in the PTEN gene, may increase the risk of developing endometrial stromal sarcoma.

The main treatment for endometrial stromal sarcoma is surgery. Depending on the stage of the cancer, this may involve removing the uterus, cervix, fallopian tubes, ovaries, and nearby lymph nodes. In some cases, radiation therapy and/or chemotherapy may also be recommended.

1. Increasing age
2. Estrogen exposure
3. Obesity
4. Tamoxifen use
5. Nulliparity (never having given birth)
6. High-dose pelvic radiation
7. Lynch syndrome
8. Cowden syndrome
9. Li-Fraumeni syndrome
10. Neurofibromatosis type 1

At this time, there is no known cure for endometrial stromal sarcoma. Treatment options may include surgery, radiation therapy, chemotherapy, and hormone therapy. Your doctor will discuss the best treatment plan for you based on the stage and type of endometrial stromal sarcoma.