Cytomegalovirus (CMV) disease is a viral infection that can cause serious health problems in people with weakened immune systems, such as those with HIV/AIDS or those who have had an organ transplant. CMV can cause a wide range of symptoms, including fever, fatigue, and enlarged lymph nodes. In some cases, it can cause serious complications, such as pneumonia, encephalitis, and hepatitis. People with impaired cell-mediated immunity, such as those with HIV/AIDS or those who have had an organ transplant, are at an increased risk of developing CMV disease.

The symptoms of Cytomegalovirus (CMV) disease in patients with impaired cell mediated immunity deemed at risk can include fever, fatigue, malaise, night sweats, weight loss, abdominal pain, diarrhea, and jaundice. Other symptoms may include headache, confusion, seizures, and encephalitis. In some cases, CMV can cause organ damage, including damage to the lungs, liver, and/or kidneys.

1. Transplantation of organs or tissues from an infected donor.
2. Receiving a blood transfusion from an infected donor.
3. Unprotected sexual contact with an infected person.
4. Sharing needles or syringes with an infected person.
5. Exposure to saliva, urine, or other body fluids from an infected person.
6. Mother-to-child transmission during pregnancy or childbirth.
7. Weakened immune system due to HIV/AIDS, cancer, or other conditions.

1. Antiviral medications: Acyclovir, Valacyclovir, and Ganciclovir are the most commonly used antiviral medications for treating CMV disease in patients with impaired cell mediated immunity.

2. Intravenous Immunoglobulin (IVIG): IVIG is a blood product that contains antibodies from healthy donors. It can help boost the immune system and reduce the severity of CMV disease.

3. Corticosteroids: Corticosteroids can help reduce inflammation and improve symptoms of CMV disease.

4. Plasma exchange: Plasma exchange is a procedure in which the patient’s blood is removed and replaced with donor plasma. This can help reduce the amount of CMV virus in the blood.

5. Bone marrow transplant: Bone marrow transplant is a procedure in which the

1. Age: Cytomegalovirus (CMV) is more common in people over the age of 40.

2. HIV/AIDS: People with HIV/AIDS are at an increased risk of developing CMV disease due to their weakened immune system.

3. Transplant recipients: People who have received an organ or bone marrow transplant are at an increased risk of developing CMV disease due to the immunosuppressive drugs they must take to prevent organ rejection.

4. Chemotherapy: People undergoing chemotherapy are at an increased risk of developing CMV disease due to the immunosuppressive effects of the drugs.

5. Blood transfusions: People who have received a blood transfusion are at an increased risk of developing CMV disease due to the potential for exposure to the virus.

6. Low white blood

Yes, there are medications available to treat Cytomegalovirus (CMV) disease in patients with impaired cell mediated immunity. These medications include ganciclovir, valganciclovir, and foscarnet. These medications are used to reduce the amount of virus in the body and help to prevent further damage to the immune system. Additionally, antiviral medications such as acyclovir and valacyclovir may be used to prevent CMV infection in patients at risk.