About Congenital stromal corneal dystrophy

What is Congenital stromal corneal dystrophy?

Congenital stromal corneal dystrophy is a rare, inherited eye disorder that affects the cornea, the clear outer layer of the eye. It is characterized by the presence of small, white, opaque spots in the cornea, which can cause vision problems. The spots are caused by an abnormal accumulation of collagen fibers in the cornea. Symptoms of the disorder usually appear in infancy or early childhood and can include blurred vision, sensitivity to light, and difficulty seeing in dim light. Treatment typically involves the use of special contact lenses or corneal transplantation.

What are the symptoms of Congenital stromal corneal dystrophy?

The most common symptoms of congenital stromal corneal dystrophy include:

-Cloudy or hazy vision

-Decreased vision

-Sensitivity to light

-Halos around lights

-Blurred vision

-Eye pain

-Redness

-Tearing

-Itching

-Swelling of the cornea

What are the causes of Congenital stromal corneal dystrophy?

Congenital stromal corneal dystrophy is a rare genetic disorder caused by mutations in the keratoepithelin (KE) gene. The KE gene is responsible for producing a protein that helps maintain the structure of the cornea. Mutations in this gene can lead to the abnormal accumulation of collagen in the cornea, resulting in corneal clouding and vision loss.

What are the treatments for Congenital stromal corneal dystrophy?

1. Corneal transplantation: This is the most effective treatment for congenital stromal corneal dystrophy. It involves replacing the affected corneal tissue with healthy donor tissue.

2. Phototherapeutic keratectomy (PTK): This procedure uses a laser to remove the abnormal corneal tissue and reshape the cornea.

3. Corneal collagen cross-linking: This procedure uses ultraviolet light and riboflavin to strengthen the cornea and reduce the risk of further damage.

4. Intacs: This procedure involves inserting tiny plastic rings into the cornea to reshape it and improve vision.

5. Corneal implants: This procedure involves implanting a synthetic material into the cornea to improve vision.

6. Corneal inlays

What are the risk factors for Congenital stromal corneal dystrophy?

1. Genetic predisposition: Congenital stromal corneal dystrophy is an inherited disorder, meaning it is passed down from parents to their children.

2. Age: The condition is usually present at birth or develops in early childhood.

3. Gender: Congenital stromal corneal dystrophy is more common in males than females.

4. Family history: Having a family history of the condition increases the risk of developing it.

5. Ethnicity: Congenital stromal corneal dystrophy is more common in people of Asian descent.

Is there a cure/medications for Congenital stromal corneal dystrophy?

At this time, there is no known cure for congenital stromal corneal dystrophy. However, there are medications that can be used to help manage the symptoms. These include topical corticosteroids, topical non-steroidal anti-inflammatory drugs, and topical cyclosporine. In some cases, surgery may be recommended to improve vision.