Congenital pseudoarthrosis of the fibula is a rare condition in which the fibula bone in the lower leg does not form properly during fetal development. This results in a weak or absent fibula bone, which can lead to instability in the ankle and lower leg. Symptoms may include pain, swelling, and deformity of the lower leg. Treatment typically involves surgery to stabilize the ankle and lower leg.

The most common symptoms of congenital pseudoarthrosis of the fibula include:
* Pain in the affected area
* Swelling
* Tenderness
* Limited range of motion
* Visible deformity of the affected area
* Weakness in the affected area
* Instability of the affected area
* A bowing of the affected area
* A clicking or grinding sensation when the affected area is moved

The exact cause of congenital pseudoarthrosis of the fibula is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Possible causes include:

• Abnormal development of the fibula during fetal development

• Abnormalities in the structure of the fibula

• Abnormalities in the blood supply to the fibula

• Trauma to the fibula during birth

• Infection or inflammation of the fibula

• Metabolic disorders

• Genetic disorders such as neurofibromatosis or Ehlers-Danlos syndrome

1. Non-surgical treatment:

- Physical therapy to improve range of motion and strength
- Bracing to provide stability
- Orthotics to improve alignment

2. Surgical treatment:

- Bone grafting to fill the gap in the fibula
- Internal fixation with screws and plates to stabilize the bone
- External fixation with pins and rods to stabilize the bone
- Bone transport to move healthy bone to the area of the pseudoarthrosis
- Osteotomy to realign the bone
- Arthrodesis to fuse the joint

1. Genetic predisposition
2. Premature birth
3. Low birth weight
4. Abnormalities of the fibula
5. Abnormalities of the surrounding soft tissue
6. Abnormalities of the adjacent joint
7. Trauma to the area
8. Infection
9. Radiation therapy
10. Systemic diseases such as diabetes, Ehlers-Danlos syndrome, and osteogenesis imperfecta

At this time, there is no known cure for congenital pseudoarthrosis of the fibula. Treatment typically involves surgical intervention, such as bone grafting, to stabilize the affected area and prevent further damage. Medications such as bisphosphonates may also be prescribed to reduce pain and inflammation. Physical therapy may also be recommended to help strengthen the muscles around the affected area.