Congenital pseudoarthrosis of the femur is a rare condition in which the femur (thigh bone) does not form properly during fetal development. This results in a weak or absent connection between the two ends of the bone, causing the bone to be unstable and unable to bear weight. Symptoms may include pain, swelling, and deformity of the affected limb. Treatment typically involves surgery to stabilize the bone and may include the use of bone grafts, metal rods, or other implants.

The most common symptoms of congenital pseudoarthrosis of the femur include:
* Pain in the affected area
* Swelling and tenderness
* Limping or difficulty walking
* A visible deformity in the affected area
* Weakness in the affected leg
* Limited range of motion in the affected leg
* A bowing of the affected leg
* A clicking or grinding sensation when the affected leg is moved

The exact cause of congenital pseudoarthrosis of the femur is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Possible causes include:

• Abnormal development of the femur during fetal development

• Abnormalities in the growth plates of the femur

• Abnormalities in the blood supply to the femur

• Abnormalities in the bone structure of the femur

• Trauma to the femur during birth

• Infection in the area of the femur

• Certain genetic disorders, such as neurofibromatosis type 1 or osteogenesis imperfecta

1. Non-surgical treatment: This includes physical therapy, bracing, and pain management.

2. Surgical treatment: This includes bone grafting, internal fixation, and distraction osteogenesis. Bone grafting involves taking a piece of bone from another part of the body and using it to fill in the gap in the femur. Internal fixation involves using metal plates and screws to hold the bone in place. Distraction osteogenesis involves slowly stretching the bone apart to encourage new bone growth.

1. Prematurity
2. Low birth weight
3. Genetic disorders
4. Abnormalities of the femur
5. Abnormalities of the growth plate
6. Abnormalities of the surrounding soft tissue
7. Trauma
8. Infection
9. Radiation therapy
10. Systemic diseases such as diabetes, rheumatoid arthritis, and Ehlers-Danlos syndrome

At this time, there is no cure for congenital pseudoarthrosis of the femur. However, there are several treatments available to help manage the condition. These include medications to reduce pain and inflammation, physical therapy to help improve mobility, and surgical procedures to help stabilize the affected area. In some cases, bone grafts may be used to help promote healing.