Congenital primary lymphedema of Gordon is a rare genetic disorder that affects the lymphatic system. It is characterized by swelling of the legs and feet due to an abnormal development of the lymphatic vessels. It is caused by a mutation in the FOXC2 gene, which is responsible for the development of the lymphatic system. Symptoms usually appear in infancy or early childhood and can include swelling of the legs and feet, thickening of the skin, and recurrent infections. Treatment typically involves compression garments, physical therapy, and medications to reduce swelling.

The symptoms of Congenital Primary Lymphedema of Gordon include:

- Swelling of the legs, feet, and/or ankles
- Skin discoloration
- Thickening of the skin
- Skin infections
- Pain and discomfort
- Difficulty walking
- Difficulty fitting into shoes
- Difficulty with hygiene due to the swelling

Congenital primary lymphedema of Gordon is a rare genetic disorder caused by mutations in the FOXC2 gene. This gene is responsible for the development of the lymphatic system, which is responsible for the drainage of fluid from the body. Mutations in this gene can lead to a disruption in the development of the lymphatic system, resulting in the accumulation of fluid in the body and the development of lymphedema. Other causes of Congenital primary lymphedema of Gordon include chromosomal abnormalities, such as trisomy 21 (Down syndrome), and certain inherited syndromes, such as Turner syndrome.

The treatments for Congenital primary lymphedema of Gordon include:

1. Compression therapy: This involves wearing compression garments such as stockings, bandages, or wraps to reduce swelling and improve lymphatic drainage.

2. Manual lymphatic drainage: This is a type of massage that helps to move lymph fluid and reduce swelling.

3. Exercise: Regular exercise can help to improve lymphatic drainage and reduce swelling.

4. Surgery: In some cases, surgery may be recommended to remove excess tissue or to create new pathways for lymphatic drainage.

5. Skin care: It is important to keep the skin clean and moisturized to prevent infection and further swelling.

6. Diet: Eating a healthy diet can help to reduce swelling and improve overall health.

The risk factors for Congenital primary lymphedema of Gordon include:

1. Family history of the condition
2. Female gender
3. Maternal diabetes
4. Maternal obesity
5. Maternal smoking
6. Maternal use of certain medications during pregnancy
7. Maternal infection during pregnancy
8. Maternal age over 35
9. Multiple pregnancies
10. Premature birth

There is no cure for Congenital primary lymphedema of Gordon, but there are treatments available to help manage the condition. These treatments include compression garments, manual lymphatic drainage, exercise, and skin care. Medications such as diuretics and antibiotics may also be prescribed to help reduce swelling and prevent infection.