Congenital generalized hypertrichosis, Ambras type (CGHA) is a rare genetic disorder characterized by excessive hair growth over the entire body. It is caused by a mutation in the HR gene, which is responsible for controlling hair growth. Symptoms typically begin at birth and may include thick, dark hair on the face, ears, arms, legs, and back. Other features may include thick eyebrows, eyelashes, and scalp hair. CGHA is inherited in an autosomal dominant pattern, meaning that only one copy of the mutated gene is needed to cause the disorder.

The symptoms of Congenital generalized hypertrichosis, Ambras type, include excessive hair growth on the face, ears, shoulders, back, and arms. The hair is usually dark and thick, and may be longer than normal. Other symptoms may include thick eyebrows, thick eyelashes, and a hairy forehead. In some cases, the hair may be so thick that it covers the eyes.

Congenital generalized hypertrichosis, Ambras type is a rare genetic disorder caused by a mutation in the AR gene. This gene is responsible for the production of androgen receptors, which are proteins that bind to androgens (male hormones) and regulate their activity. Mutations in the AR gene can lead to an overproduction of androgens, resulting in excessive hair growth. Other causes of Congenital generalized hypertrichosis, Ambras type may include environmental factors, such as exposure to certain chemicals or radiation, or a combination of genetic and environmental factors.

1. Laser hair removal: This is the most common treatment for Congenital generalized hypertrichosis, Ambras type. It involves using a laser to target and destroy the hair follicles, thus reducing the amount of hair growth.

2. Electrolysis: This is a more invasive treatment option that involves using an electric current to destroy the hair follicles.

3. Topical medications: There are several topical medications that can be used to reduce hair growth, such as minoxidil and eflornithine.

4. Surgery: In some cases, surgery may be necessary to remove the excess hair.

5. Hormone therapy: Hormone therapy may be used to reduce the amount of androgens (male hormones) in the body, which can help reduce hair growth.

1. Genetic mutation: Congenital generalized hypertrichosis, Ambras type is caused by a mutation in the gene HR (hairy-related) on chromosome 17.

2. Family history: This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.

3. Ethnicity: This condition is more common in individuals of Hispanic descent.

At this time, there is no known cure for Congenital generalized hypertrichosis, Ambras type. However, there are medications that can be used to reduce the amount of hair growth. These medications include topical minoxidil, oral finasteride, and topical eflornithine. Additionally, laser hair removal and electrolysis can be used to reduce the amount of hair growth.