About Congenital bilateral absence of vas deferens

What is Congenital bilateral absence of vas deferens?

Congenital bilateral absence of vas deferens is a rare condition in which the vas deferens, the tubes that carry sperm from the testicles to the penis, are missing from birth. This condition can cause infertility in men, as sperm are unable to be ejaculated. Treatment options include assisted reproductive technology, such as in vitro fertilization (IVF).

What are the symptoms of Congenital bilateral absence of vas deferens?

The symptoms of Congenital bilateral absence of vas deferens include:

-Infertility
-Low sperm count
-Painful ejaculation
-Abnormal semen analysis
-Abnormal semen volume
-Abnormal semen consistency
-Abnormal semen color
-Abnormal semen pH
-Abnormal semen motility
-Abnormal semen morphology
-Abnormal semen viscosity
-Abnormal semen agglutination
-Abnormal semen fructose levels
-Abnormal semen zinc levels

What are the causes of Congenital bilateral absence of vas deferens?

1. Genetic mutations: Congenital bilateral absence of the vas deferens (CBAVD) is usually caused by genetic mutations in the CFTR gene, which is responsible for the production of a protein that helps regulate the movement of salt and water in and out of cells.

2. Cystic Fibrosis: CBAVD is often associated with cystic fibrosis, a genetic disorder that affects the lungs, pancreas, and other organs.

3. Unknown Causes: In some cases, the cause of CBAVD is unknown.

What are the treatments for Congenital bilateral absence of vas deferens?

1. Surgical reconstruction: This involves surgically reconstructing the vas deferens using a segment of the spermatic cord or a segment of the intestine.

2. Testicular sperm extraction (TESE): This involves surgically extracting sperm from the testicles and using it for in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).

3. Epididymal sperm aspiration (ESA): This involves surgically aspirating sperm from the epididymis and using it for IVF or ICSI.

4. Donor sperm: This involves using donor sperm for IVF or ICSI.

What are the risk factors for Congenital bilateral absence of vas deferens?

1. Family history of cystic fibrosis
2. Mutation in the CFTR gene
3. Exposure to certain environmental toxins
4. Smoking
5. Obesity
6. Advanced paternal age
7. Use of certain medications, such as anabolic steroids

Is there a cure/medications for Congenital bilateral absence of vas deferens?

At this time, there is no cure for congenital bilateral absence of the vas deferens. However, there are treatments available to help men with this condition father a child. These treatments include assisted reproductive technologies such as in vitro fertilization (IVF) and intracytoplasmic sperm injection (ICSI). Additionally, medications such as testosterone replacement therapy and gonadotropin-releasing hormone (GnRH) agonists may be used to help increase sperm production.