COG7-CDG is a non-profit organization that works to promote the development of the global economy through the use of digital technologies. The organization works to create a platform for collaboration between governments, businesses, and civil society to promote the use of digital technologies to drive economic growth.

The symptoms of COG7-CDG vary from person to person, but can include: developmental delay, intellectual disability, seizures, Hypotonia (low muscle tone), Ataxia (lack of muscle coordination), vision and hearing problems, feeding difficulties, and growth delays. Other symptoms may include facial dysmorphism, cardiac defects, and skeletal abnormalities.

COG7-CDG is caused by mutations in the COG7 gene. This gene provides instructions for making a protein that is involved in the formation of a complex called the COG complex. The COG complex is involved in the transport of proteins within cells. Mutations in the COG7 gene lead to a deficiency of the COG complex, which disrupts the transport of proteins and causes the signs and symptoms of COG7-CDG.

The treatments for COG7-CDG vary depending on the individual and the severity of the condition. Treatment may include dietary modifications, physical therapy, occupational therapy, speech therapy, and medications to help manage symptoms. In some cases, enzyme replacement therapy may be recommended. Additionally, genetic counseling may be recommended to help families understand the condition and its implications.

The risk factors for COG7-CDG include:

1. Family history of the disorder
2. Mutation in the COG7 gene
3. Consanguinity (marriage between close relatives)
4. Advanced maternal age
5. Exposure to certain environmental toxins or medications during pregnancy.

At this time, there is no cure for COG7-CDG. However, there are medications that can help manage the symptoms of the disorder. These medications include anticonvulsants, anti-inflammatory drugs, and vitamins. Additionally, physical and occupational therapy can help improve motor skills and coordination.