Cat-eye syndrome is a rare genetic disorder caused by a chromosomal abnormality. It is characterized by a variety of physical and developmental abnormalities, including an abnormally shaped eye (cat-eye shape), heart defects, and intellectual disability. It is caused by a chromosomal abnormality known as an inverted duplication of chromosome 22.

The most common symptoms of Cat-eye syndrome include:
* Abnormal eye shape (coloboma)
* Abnormalities of the heart, kidneys, and other organs
* Low birth weight
* Cleft lip and/or palate
* Abnormalities of the genitalia
* Abnormalities of the skeleton
* Mental retardation
* Speech and language delays
* Hearing loss
* Seizures
* Abnormalities of the face and head
* Abnormalities of the hands and feet
* Abnormalities of the urinary tract
* Abnormalities of the gastrointestinal tract
* Abnormalities of the immune system

Cat-eye syndrome is caused by a chromosomal abnormality known as an inverted duplication of chromosome 22. This abnormality occurs when a piece of chromosome 22 breaks off and attaches itself to the end of another chromosome, resulting in an extra copy of the genetic material found on the end of the chromosome.

The treatments for Cat-eye syndrome vary depending on the individual and the severity of the condition. Treatment may include:

1. Surgery to correct any physical abnormalities, such as cleft lip or palate, or to correct any vision problems.

2. Speech therapy to help with any speech delays or difficulties.

3. Physical therapy to help with any physical delays or difficulties.

4. Occupational therapy to help with any fine motor skills or coordination issues.

5. Behavioral therapy to help with any behavioral issues.

6. Special education services to help with any learning disabilities.

7. Genetic counseling to help families understand the condition and its implications.

The primary risk factor for Cat-eye syndrome is having a parent who carries a chromosomal abnormality known as an inverted duplication of chromosome 22. This abnormality is caused by a rearrangement of genetic material during the formation of reproductive cells. Other risk factors include having a family history of the condition, being of a certain ethnic background, and being born prematurely.

There is no cure for Cat-eye syndrome, but there are medications that can help manage some of the symptoms. These include medications to help with vision problems, hearing problems, and seizures. Additionally, physical and occupational therapy can help with motor skills and other developmental delays.