Caroli disease is a rare congenital disorder that affects the bile ducts of the liver. It is characterized by the abnormal dilatation of the intrahepatic bile ducts, which can lead to liver damage and cirrhosis. Symptoms may include abdominal pain, jaundice, and fever. Treatment typically involves surgical removal of the affected bile ducts.

The most common symptoms of Caroli Disease include:

-Pain in the abdomen
-Fever
-Nausea and vomiting
-Weight loss
-Jaundice
-Dark urine
-Itchy skin
-Enlarged liver
-Enlarged gallbladder
-Abdominal swelling
-Abdominal tenderness
-Abdominal mass
-Abdominal pain
-Diarrhea
-Fatigue

Caroli Disease is a rare congenital disorder caused by a genetic mutation. It is caused by a mutation in the CFTR gene, which is responsible for the production of a protein that helps regulate the flow of salt and water in and out of cells. Other causes of Caroli Disease include environmental factors, such as exposure to certain toxins, and certain lifestyle factors, such as smoking.

The main treatment for Caroli Disease is surgical intervention. This may involve removing the affected parts of the bile ducts, or performing a liver transplant. Other treatments may include medications to reduce inflammation, antibiotics to treat infections, and dietary changes to reduce fat intake. In some cases, a stent may be placed in the bile ducts to help keep them open.

1. Autosomal recessive inheritance
2. Family history of Caroli Disease
3. Congenital hepatic fibrosis
4. Cystic kidney disease
5. Polycystic kidney disease
6. Congenital heart defects
7. Biliary atresia
8. Choledochal cysts
9. Intrahepatic bile duct dilatation
10. Abnormalities of the pancreas

There is no cure for Caroli Disease, but medications can be used to help manage symptoms. These medications may include diuretics, antibiotics, and anti-inflammatory drugs. In some cases, surgery may be necessary to remove blockages in the bile ducts.