Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) is a rare genetic disorder that affects the eyes. It is characterized by inflammation of the retina and vitreous, as well as the formation of abnormal blood vessels in the eye. Symptoms of ADNIV include decreased vision, floaters, and flashes of light. Treatment typically involves laser therapy, intravitreal injections, and vitrectomy.

The symptoms of Autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) include:

-Decreased vision
-Floaters
-Flashes of light
-Distorted vision
-Retinal detachment
-Vitreous hemorrhage
-Macular edema
-Retinal neovascularization
-Retinal pigment epithelial detachment
-Vitreous inflammation

The exact cause of autosomal dominant neovascular inflammatory vitreoretinopathy (ADNIV) is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Mutations in the TNFRSF10A gene have been identified as a cause of ADNIV. This gene is involved in the regulation of inflammation and cell death. Other genetic factors, such as mutations in the TNFRSF10B gene, may also be involved. Environmental factors, such as exposure to certain toxins or infections, may also play a role in the development of ADNIV.

1. Laser photocoagulation: This is a procedure that uses a laser to seal off leaking blood vessels in the retina.

2. Intravitreal injections: This involves injecting medications directly into the vitreous cavity of the eye to reduce inflammation and prevent further damage.

3. Vitrectomy: This is a surgical procedure that removes the vitreous gel from the eye and replaces it with a gas bubble or silicone oil.

4. Anti-inflammatory medications: These medications can help reduce inflammation and prevent further damage to the retina.

5. Corticosteroids: These medications can help reduce inflammation and prevent further damage to the retina.

1. Family history of autosomal dominant neovascular inflammatory vitreoretinopathy
2. Genetic mutations in the VEGFA gene
3. Age (most commonly seen in young adults)
4. Systemic inflammatory diseases such as rheumatoid arthritis, systemic lupus erythematosus, and inflammatory bowel disease
5. Certain medications such as corticosteroids and immunosuppressants
6. Trauma to the eye

At this time, there is no known cure for autosomal dominant neovascular inflammatory vitreoretinopathy. However, there are medications that can be used to manage the symptoms and slow the progression of the disease. These medications include corticosteroids, non-steroidal anti-inflammatory drugs (NSAIDs), and immunosuppressants. Additionally, laser therapy and vitrectomy surgery may be used to treat some of the complications associated with the disease.