About Autosomal dominant keratitis

What is Autosomal dominant keratitis?

Autosomal dominant keratitis is a rare genetic disorder that affects the cornea of the eye. It is caused by a mutation in the gene that codes for the protein keratin, which is responsible for the structure and strength of the cornea. Symptoms of this disorder include blurred vision, sensitivity to light, and eye pain. Treatment typically involves the use of topical medications and/or surgery.

What are the symptoms of Autosomal dominant keratitis?

The most common symptoms of Autosomal dominant keratitis include:

-Painful, red eyes
-Blurred vision
-Sensitivity to light
-Excessive tearing
-Crusting of the eyelids
-Corneal ulcers
-Corneal scarring
-Corneal opacities
-Decreased vision

What are the causes of Autosomal dominant keratitis?

The exact cause of autosomal dominant keratitis is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Possible causes include exposure to ultraviolet light, trauma, infection, and certain medications.

What are the treatments for Autosomal dominant keratitis?

1. Topical lubricants: Artificial tears, gels, and ointments can help reduce dryness and irritation.

2. Topical antibiotics: Antibiotic eye drops or ointments can help reduce inflammation and infection.

3. Corticosteroids: Steroid eye drops or ointments can help reduce inflammation.

4. Surgery: In some cases, surgery may be necessary to remove scar tissue or to repair the cornea.

5. Phototherapeutic keratectomy: This procedure uses a laser to remove the outer layer of the cornea and reduce scarring.

6. Corneal transplant: In severe cases, a corneal transplant may be necessary to restore vision.

What are the risk factors for Autosomal dominant keratitis?

1. Family history of the condition
2. Exposure to ultraviolet light
3. Contact lens wear
4. Certain medical conditions, such as diabetes
5. Certain medications, such as corticosteroids
6. Trauma to the eye
7. Certain genetic mutations, such as those associated with the TGFBI gene

Is there a cure/medications for Autosomal dominant keratitis?

Yes, there are treatments available for autosomal dominant keratitis. These include topical medications such as corticosteroids, antibiotics, and anti-inflammatory agents, as well as surgical interventions such as corneal transplantation.