Arthrogryposis Multiplex Congenita (AMC) is a rare congenital disorder characterized by multiple joint contractures (stiffness) and muscle weakness. It is caused by abnormal development of the fetus in the womb, resulting in limited movement of the joints. Symptoms vary from person to person and can range from mild to severe. Treatment typically includes physical therapy, occupational therapy, and sometimes surgery.

The symptoms of Arthrogryposis Multiplex Congenita (AMC) vary from person to person, but can include:

- Joint contractures (stiffness) in two or more areas of the body

- Low muscle tone

- Abnormal positioning of the arms and legs

- Limited range of motion in the joints

- Abnormal curvature of the spine

- Abnormal facial features

- Clubfoot

- Cleft palate

- Abnormalities of the hands and feet

- Abnormalities of the eyes, ears, and other organs

Arthrogryposis Multiplex Congenita (AMC) is a rare condition that affects the development of muscles and joints. The exact cause of AMC is unknown, but it is believed to be caused by a combination of genetic and environmental factors. Possible causes include:

1. Genetic mutations: Certain genetic mutations can cause AMC. These mutations can be inherited from a parent or can occur spontaneously.

2. Abnormal fetal development: Abnormal development of the fetus in the womb can lead to AMC. This can be caused by a variety of factors, including infections, exposure to certain medications or toxins, or a lack of nutrients.

3. Nerve damage: Damage to the nerves that control muscle movement can lead to AMC. This can be caused by a variety of factors, including infections, trauma, or a lack of oxygen during

1. Physical therapy: Physical therapy is the mainstay of treatment for Arthrogryposis Multiplex Congenita (AMC). Physical therapy helps to improve range of motion, strength, and function of the affected joints.

2. Surgery: Surgery may be recommended to improve range of motion and function of the affected joints. Surgery may include tendon transfers, joint releases, and joint fusions.

3. Orthotics: Orthotics, such as splints, braces, and casts, may be used to help support and protect the affected joints.

4. Occupational therapy: Occupational therapy can help improve function and independence with activities of daily living.

5. Assistive devices: Assistive devices, such as wheelchairs, walkers, and canes, may be used to help with mobility.

1. Maternal diabetes
2. Maternal infection
3. Maternal use of certain medications
4. Maternal exposure to environmental toxins
5. Genetic mutations
6. Chromosomal abnormalities
7. Fetal malformations
8. Fetal growth restriction
9. Placental insufficiency
10. Uterine abnormalities

There is no cure for Arthrogryposis Multiplex Congenita, but there are treatments available to help manage the condition. These treatments may include physical therapy, occupational therapy, orthopedic surgery, and medications to help manage pain and muscle spasms.