Acute myeloid leukaemia with myelodysplasia-related features (AML-MDS) is a type of acute myeloid leukaemia (AML) that is associated with features of myelodysplastic syndrome (MDS). It is a rare form of AML that is characterized by the presence of abnormal cells in the bone marrow and peripheral blood. Patients with AML-MDS typically have a poor prognosis and require aggressive treatment.

The symptoms of Acute myeloid leukaemia with myelodysplasia-related features can include:

- Fatigue
- Shortness of breath
- Pale skin
- Easy bruising or bleeding
- Fever
- Weight loss
- Bone or joint pain
- Swollen lymph nodes
- Abdominal pain
- Night sweats
- Loss of appetite
- Increased risk of infection

The exact cause of acute myeloid leukaemia with myelodysplasia-related features is unknown. However, it is believed to be caused by a combination of genetic and environmental factors. Genetic factors may include inherited mutations in certain genes, such as those involved in DNA repair, cell cycle control, and apoptosis. Environmental factors may include exposure to certain chemicals, radiation, or viruses.

1. Chemotherapy: This is the main treatment for AML with myelodysplasia-related features. Chemotherapy drugs are used to kill the cancer cells and stop them from growing.

2. Targeted therapy: This type of treatment uses drugs that target specific molecules involved in the growth and spread of cancer cells.

3. Stem cell transplant: This is a procedure in which healthy stem cells are transplanted into the patient to replace the cancerous cells.

4. Radiation therapy: This type of treatment uses high-energy radiation to kill cancer cells.

5. Clinical trials: Clinical trials are research studies that test new treatments for AML with myelodysplasia-related features.

1. Age: Most cases of AML with myelodysplasia-related features occur in people over the age of 60.

2. Exposure to radiation: People who have been exposed to high doses of radiation, such as those who have had radiation therapy for cancer, are at an increased risk of developing AML with myelodysplasia-related features.

3. Certain genetic conditions: People with certain genetic conditions, such as Down syndrome, are at an increased risk of developing AML with myelodysplasia-related features.

4. Certain medications: People who take certain medications, such as chemotherapy drugs, are at an increased risk of developing AML with myelodysplasia-related features.

5. Exposure to certain chemicals: People who have been exposed to certain chemicals, such

Yes, there are treatments available for Acute myeloid leukaemia with myelodysplasia-related features. Treatment options may include chemotherapy, radiation therapy, stem cell transplant, targeted therapy, and supportive care. Your doctor will discuss the best treatment plan for you based on your individual situation.