Acrofacial dysostosis, Kennedy-Teebi type is a rare genetic disorder characterized by facial abnormalities, skeletal malformations, and intellectual disability. It is caused by a mutation in the gene encoding the transcription factor TBX1. Symptoms may include cleft lip and/or palate, low-set ears, wide-set eyes, and a small lower jaw. Other features may include hearing loss, heart defects, and kidney abnormalities. Treatment is based on the individual's symptoms and may include surgery, speech therapy, and physical therapy.

The symptoms of Acrofacial dysostosis, Kennedy-Teebi type, include:

-Cleft lip and/or palate
-Abnormalities of the ears, including small, low-set ears
-Abnormalities of the eyes, including small eyes, droopy eyelids, and/or strabismus
-Abnormalities of the hands and feet, including short fingers and toes, and/or syndactyly
-Delayed development of motor skills
-Delayed development of speech and language
-Intellectual disability
-Heart defects
-Kidney abnormalities
-Hearing loss

Acrofacial dysostosis, Kennedy-Teebi type is a rare genetic disorder caused by mutations in the gene known as PORCN. This gene is responsible for the production of a protein that is essential for the development of the face, hands, and feet. Mutations in this gene can lead to a variety of physical and developmental abnormalities, including cleft lip and palate, malformed ears, and webbed fingers and toes. Other symptoms may include intellectual disability, hearing loss, and vision problems.

1. Surgery: Surgery is often used to correct the facial deformities associated with Acrofacial dysostosis, Kennedy-Teebi type. This may include reconstructive surgery to correct the cleft lip and palate, as well as other facial deformities.

2. Orthodontic Treatment: Orthodontic treatment may be used to correct the malocclusion (misalignment of the teeth) associated with Acrofacial dysostosis, Kennedy-Teebi type.

3. Speech Therapy: Speech therapy may be used to help individuals with Acrofacial dysostosis, Kennedy-Teebi type to improve their speech and communication skills.

4. Physical Therapy: Physical therapy may be used to help individuals with Acrofacial dysostosis, Kennedy-Teebi type to improve their

1. Autosomal recessive inheritance
2. Mutations in the gene PORCN
3. Maternal diabetes
4. Maternal exposure to certain medications or toxins
5. Maternal alcohol consumption
6. Maternal smoking
7. Maternal obesity
8. Advanced maternal age

At this time, there is no known cure for Acrofacial dysostosis, Kennedy-Teebi type. However, there are medications and treatments available to help manage the symptoms. These include physical therapy, occupational therapy, speech therapy, orthodontic treatment, and surgery. Additionally, medications such as anticonvulsants, muscle relaxants, and anti-inflammatory drugs may be prescribed to help manage the symptoms.